Nuclear Receptors in Breast Cancer
Researchers from the Nuclear Receptors in Breast Cancer (NRBC) project are currently engaged in the analysis of two breast cancer cohorts through detailed characterisation of the molecular biology of nuclear receptors in oestrogen receptor (ER) positive and negative invasive ductile carcinomas.
QFAB researchers are participating in this effort by developing customised computational methods for analysing and visualising the results of PCR based low-density array experiments.
In addition to the use of molecular profiling results for sample clustering and cohort heterogeneity analysis, QFAB has developed a network construction toolbox for extracting the local networks of nuclear receptors from large public data repositories.
QFAB has also provided training to researchers within the NRBC project in the use of network analysis tools, demonstrating the power of these approaches in the analysis and visualisation experimental results.
Molecular Biology Case Studies
